Drug development that cares
Tuning the injectability and release properties of microparticles starts with controlling their exact size, shape, and surface area. IamFluidics’ high-yield and high-quality microencapsulation processes are a perfect match to this end. We are developing the ApiBead™ platform to tailor microbead properties for the controlled delivery of active pharmaceutical ingredients (APIs).
The advantage of monodispersity
Monodisperse or uniformly sized microparticles offers various advantages over polydisperse ones. Specifically, particle size distributions have a significant effect on their injectability,[1] flowability,[2] and release profile.[3] In other words, narrowing the size distribution of microparticles enhances the administration and delivery of the microencapsulated API.
[1] Sarmadi et al., Science Adv., 2020, 6, eabb6594.
[2] Liu et al., Int. J. Pharm., 2008, 362, 109.
[3] Berkland et al., J. Control. Release, 2002, 82, 137.
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