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The advantage of monodispersity

Monodisperse or uniformly sized microparticles offer various advantages over polydisperse ones. Spherical monodisperse particles, combined with a tightly controlled particle size distribution have a significant positive effect on injectability1, flowability2 and release profiles3. With these three key attributes the delivery and performance of APIs can be enhanced.

ApiBead™ is developed to deliver just that: monodisperse, perfectly shaped spheres with a tuneable controlled particle size distribution at CV<10%:


1. Sarmadi et al., Science Adv., 2020, 6, eabb6594.
2. Liu et al., Int. J. Pharm., 2008, 362, 109.
3. Berkland et al., J. Control. Release, 2002, 82, 137.

Source: IamFluidics

Scalable & Sustainable

  • With our continuous microfluidic process, we create monodisperse microparticles in the air, free of oils and surfactants.
  • The process uses less toxic solvents (class 3) than conventional processes.
  • Our perfect spheres are produced at jet speed (ml/min), chip-free and a 1000 times faster than conventional microfluidic systems.
  • Production is conducted under strict in-line control, tuneable for particle size, material choice and sphere morphology fit for you API.
  • The process is scalable for both R&D and pre-clinical purposes at g/day and clinical and commercial purposes kg/day with waste minimization and yield optimization in mind.


A world of potential


Microparticle structures


Solid Matrix

Solid Matrix

Solid Matrix

Solid Matrix

Solid Matrix

Solid Matrix


  • Capsules / Single core-shell
  • Matrix-type / Multi core-shell
  • Simple solid particles
  • (Pickering) emulsions
  • Liquified (soft) capsules
  • Complex structures



  • PLGA / PLA
  • Polysaccharides
  • Lipids
  • Waxes
  • Collagen / Gelatin
  • PMMA


  • Hydrophobic
  • Hydrophilic
  • Small molecules
  • Nucleotides
  • Peptides
  • Proteins

* These lists are exemplary and non-exhaustive. Please contact us to discuss your API or excipient of interest.

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